KAMPALA, Uganda, 16 April 2025 /African Media Agency (AMA)/- Ahead of World Malaria Day , Target Malaria, a not-for-profit research consortium pioneering genetic technologies for malaria control, hosted a live demonstration this month of its educational video game, Target Malaria: The Game . This interactive tool is reshaping how science is communicated by making complex genetic technologies accessible, engaging, and fun.
Originally launched at the end of 2024, the educational game places players in the role of a lab technician working on genetically modified mosquitoes — a potential tool for vector control being explored to eliminate malaria in Africa. It introduces players of all ages and backgrounds to the real-world tools and processes of molecular biology through two modules: “Microinjection” and “Transgenic Screening.”
In “Microinjection”, players simulate injecting a DNA solution into mosquito embryos, and in “Transgenic Screening”, players sort fluorescent, genetically modified mosquito larvae.
This goes beyond being merely a game—it's a tool designed to build skills," explains Louise Marston, Senior Research Technician for Target Malaria at the Crisanti Lab of Imperial College London, who came up with the concept of this game. "By using a digital format, we're showing how scientific discoveries can be brought vividly to life, including in areas with limited internet access.
A tool developed for easy accessibility
Developed with independent game developer Michael Marston, the game was designed to work on low-spec systems and in low-bandwidth environments — critical for areas where internet access is limited or unreliable. This makes it a powerful tool for science educators and trainers working beyond urban centres in Africa and beyond.
According to a recent report Africa’s video game sector is currently the quickest expanding globally, boasting more than 186 million players continent-wide as of 2024. Most of these gamers are younger than 30 years old, presenting a significant chance to enlighten, motivate, and interact with prospective scientists through mediums they already love.
"Gaming is a medium that resonates with younger generations. Target Malaria: The Game leverages this engagement to ignite curiosity, provide an introduction to molecular biology, and enhance scientific understanding," says Marston.
A fresh horizon for stakeholder involvement
Target Malaria: The Game forms part of an extensive collection of creative resources employed by Target Malaria to raise awareness about the possibilities of genetic alteration in controlling malaria and their developing gene drive technology. Other tools include items such as " Mozzie Drive (a card game), Swarm Participating in this sound art 'sonification' experience and interactive theater initiatives in places such as Burkina Faso, the game is aiding in building trust, enhancing transparency, and fostering comprehension amongst various communities and stakeholders.
Target Malaria frequently organizes science café sessions where these tools are showcased to communities affected by and particularly susceptible to malaria.
We urge universities, schools, and laboratories to embrace this tool for more than just raising awareness; use it for education as well. This approach moves the laboratory setting directly into classrooms, helping to dispel numerous misunderstandings regarding science and biotechnology," remarks Jean Birba, the Stakeholder Engagement Officer at Target Malaria Burkina Faso.
Target Malaria: The Game It can be accessed in English and French and operates smoothly on high-end gaming PCs as well as lower-specced devices. The research group plans to release a Beta version for Mac and introduce a mobile edition soon.
"Involve stakeholders at every level is crucial for our method towards accountable research. This game showcases our dedication to openness, inclusiveness, and learning about gene drive tech in combating malaria. Our aim is to connect with as wide an audience as we can and motivate them to download, play, and spread the word," states Birba.
Notes to editors:
How to download “Target Malaria: The Game”
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Download the game from Target Malaria’s page on Itch.io:
https://targetmalaria.itch.io/target-malaria-the-game
Open the downloaded file “TargetMalariaTheGameInstaller” and execute it.A pop-up window titled "The Game Setup Wizard" will show up on your screen. Agree to the license terms and press Next multiple times. If you wish to add a shortcut to your desktop, tick the corresponding checkbox prior to clicking “Finish”.
The game will start up automatically once the installation is complete. Choose your desired options.
language and play!
Digital Asset
Distributed by African Media Agency in representation of Target Malaria
About Target Malaria
Target Malaria is an international non-profit organization dedicated to developing and sharing innovative, affordable, and lasting genetic methods to alter mosquito populations and decrease the spread of malaria. Our objective is to help create a globe where malaria no longer exists. We strive for exceptional standards across all our activities, paving the way for ethical research and advancement in genetic technologies like gene drive. www.targetmalaria.org
The primary financial support for Target Malaria comes from the Bill & Melinda Gates Foundation and Open Philanthropy. The main recipient of these funds is Imperial College London, working alongside collaborators across Africa, Europe, and North America.
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